Frequency and determinants of use of immunosuppressants in the Australian Scleroderma Cohort Study

Abstract

Objectives: To assess the frequency and determinants of immunosuppressant medication use in systemic sclerosis and changes in prescribing patterns over time. Methods: The Australian Scleroderma Cohort Study participants meeting the American College of Rheumatology/European Alliance of Associations for Rheumatology criteria for systemic sclerosis with recorded treatment data were included. The Chi-square, two-sample t-tests or Wilcoxon rank-sum tests were used for between-group comparison as appropriate. Multivariable logistic regression models were used to establish the determinants of the use of immunosuppressants. Results: Of 2019 participants, 60% received immunosuppressants, including 81..